A white blood cell policeman, with the help of a cold pill, must stop a deadly virus from destroying the human they live in, Frank.
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Chris Rock
Osmosis Jones (voice)
Laurence Fishburne
Thrax (voice)
David Hyde Pierce
Drix (voice)
Brandy Norwood
Leah (voice)
Elena Franklin
Shane Detorre
Bill Murray
Frank Detorre
William Shatner
Mayor Phlegmming (voice)
Ron Howard
Tom Colonic (voice)
Kid Rock
Kidney Rock (voice)
Molly Shannon
Mrs. Boyd
Chris Elliott
Bob
Jonathan Adams
Officer Tom (voice)
Carlos Alazraqui
Spanish Germ (voice)
Keith Anthony
Additional Character Voices (voice)
Eddie Barth
Conductor (voice)
Peter Farrelly
Director, Producer
Bobby Farrelly
Director, Producer
Tom Sito
Co-Director
Piet Kroon
Co-Director
Marc Hyman
Writer
Zak Penn
Producer
Bradley Thomas
Producer
Dennis Edwards
Producer
Mark Irwin
Director of Photography
Randy Edelman
Original Music Composer
Stephen Schaffer
Editor
Sam Seig
Editor
Lois Freeman-Fox
Editor
Pamela Withers
Costume Design
Sydney J. Bartholomew Jr.
Production Design
