Retroville becomes ground zero for a meteor engraved with a mysterious alien message, which only the best and brightest(naturally, Jimmy) can translate. When he finally figures the message out, he and his friends are teleported into deep space and are forced to become contestants on an intergalactic reality game show, where the losers have their home planets destroyed.
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Debi Derryberry
Jimmy Neutron / Alien Actress / Alien Woman (voice)
Rob Paulsen
Carl Wheezer/Mr. Wheezer/Mrs. Wheezer/Test Pilot/Announcer (voice)
Jeffrey Garcia
Sheen Estevez / Army Guard (voice)
Frank Welker
Goddard (voice)
Carolyn Lawrence
Cindy Vortex (voice)
Crystal Scales
Libby Folfax (voice)
Tim Allen
Meldar Prime (voice)
Alyssa Milano
April (voice)
Carlos Alazraqui
Sr. Estevez (voice)
Jeff Bennett
Gorlock #2 / Brain #1 (voice)
Megan Cavanagh
Judy Neutron / Mrs. Vortex (voice)
Jim Cummings
Brain #2 / Mayor Quadar (voice)
Mark DeCarlo
Hugh Neutron / Emergency System / Gen. Abercrombie (voice)
Jess Harnell
Meldar Prime (singing voice)
Joe Lala
Sr. Estevez (voice)
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