Jimmy is a young man who was born without an immune system and has lived his life within a plastic bubble in his bedroom... who pines for the sweet caresses of girl-next-door Chloe. But when Chloe decides to marry her high school boyfriend, Jimmy – bubble suit and all – treks cross-country to stop her.
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Jake Gyllenhaal
Jimmy Livingston
Swoosie Kurtz
Mrs. Livingston
Marley Shelton
Chloe
Danny Trejo
Slim
John Carroll Lynch
Mr. Livingston
Verne Troyer
Dr. Phreak
Dave Sheridan
Mark
Brian George
Pushpop
Patrick Cranshaw
Pappy / Pippy
Stephen Spinella
Chicken Man
Ever Carradine
Lisa, Mark's Sister
Geoffrey Arend
Flipper Boy
Beetlejuice
Li'l Zip
Matthew McGrory
Human Sasquatch
Bonnie Morgan
Rubber Woman
